SCHEMBL21979746

SCHEMBL21979746

C[SiH2]C1(C=C(C)c2ccccc2)CCCCO1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.36
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031018 0.76 KDM1A (0.38) KDM1ACES2CES1
SCHEMBL9311411 0.76 GLA (0.33)
SCHEMBL7523581 0.73 KDM1A (0.36) KDM1ACES2CES1
SCHEMBL4879093 0.67 KDM1A (0.33) KDM1A
SCHEMBL3261130 0.67
SCHEMBL27582908 0.66
SCHEMBL28108529 0.65
SCHEMBL3417765 0.65
SCHEMBL116500 0.65 DPP4 (0.35)
SCHEMBL27569246 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108778443-B Antifoam compositions for detergents 瓦克化学股份公司 2021-10-29 CN disclosed
US-10870732-B2 Defoamer compositions for detergents WACKER CHEMIE AG (DE) 2020-12-22 US disclosed
US-20200165393-A1 DEFOAMER COMPOSITIONS FOR DETERGENTS WACKER CHEMIE AG (DE) 2020-05-28 US disclosed
CN-108778443-A defoaming agent composition for detergent 瓦克化学股份公司 2018-11-09 CN disclosed