SCHEMBL2198022

SCHEMBL2198022

[O]CCOCCOCCOCCO

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
TSHR P16473 2/20 0.62
MAPK1 P28482 1/20 0.62
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 1/20 0.43
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990618 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL2921920 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL384511 0.97
SCHEMBL45160 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL5135405 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL4092706 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL12157423 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19000749 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL12865309 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL3359595 0.83 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5965598-A PHOTOTHERAPEUTIC AND PHOTODIAGNOSTIC AGENTS AS FREE MOLECULES AND AS CONJUGATES WITH MACROMOLECULAR CARRIER MOLECULES MOLTENI L. & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) 1999-10-12 US claimed
EP-0906758-A1 Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents MOLTENI L. & C. dei Fratelli Alitti Società di Esercizio S.P.A. (IT) 1999-04-07 EP claimed
CN-117794929-A Selective BCL-XL PROTAC compounds and methods of use 法国施维雅药厂 2024-03-29 CN disclosed
CN-107709342-B Process for preparing acetylgalactosamine acid derivatives 豪夫迈·罗氏有限公司 2021-09-03 CN disclosed
CN-113164775-A Polycyclic compounds and methods for rapid accelerated targeted degradation of fibrosarcoma polypeptides 阿尔维纳斯运营股份有限公司 2021-07-23 CN disclosed
CN-108738321-B GalNAc cluster phosphoramidites 豪夫迈·罗氏有限公司 2021-06-11 CN disclosed
CN-108738321-A9 GalNAc cluster phosphoramidites 豪夫迈·罗氏有限公司 2021-01-29 CN disclosed
EP-1719794-B1 NOVEL POLYMERS AND USES THEREOF MITSUI CHEMICALS INC (JP) 2017-01-04 EP disclosed
CN-1914253-B Polymer and use thereof MITSUI CHEMICALS INC 2011-08-31 CN disclosed
US-7977429-B2 Polymers and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-07-12 US disclosed
CN-101817929-A Novel polymers and uses thereof MITSUI CHEMICALS INC 2010-09-01 CN disclosed
US-20070154431-A1 Novel polymers and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-07-05 US disclosed
CN-1914253-A Novel polymers and uses thereof MITSUI CHEMICALS INC (JP) 2007-02-14 CN disclosed
EP-1719794-A1 NOVEL POLYMERS AND USES THEREOF Mitsui Takeda Chemicals, Inc. (JP) 2006-11-08 EP disclosed
US-5965598-A PHOTOTHERAPEUTIC AND PHOTODIAGNOSTIC AGENTS AS FREE MOLECULES AND AS CONJUGATES WITH MACROMOLECULAR CARRIER MOLECULES MOLTENI L. & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) 1999-10-12 US disclosed
EP-0906758-A1 Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents MOLTENI L. & C. dei Fratelli Alitti Società di Esercizio S.P.A. (IT) 1999-04-07 EP disclosed
CN-1176644-A Lewis X derivative and process for producing the same SUMITOMO PHARMA (JP) 1998-03-18 CN disclosed
EP-0801071-A1 LEWIS X DERIVATIVE AND PROCESS FOR PRODUCING THE SAME SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1997-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154431-A1 Novel polymers and uses thereof RAD54L, VCL, TYR MEN1 4310/4885KMT2A 1714/4885TSHR 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.