⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22122714 | 0.98 | GBA1 (0.33) | — | |
| SCHEMBL11438137 | 0.82 | — | — | |
| SCHEMBL9784324 | 0.82 | MAPT (0.32) | — | |
| SCHEMBL2911557 | 0.80 | — | — | |
| SCHEMBL9583103 | 0.80 | — | — | |
| SCHEMBL4042067 | 0.80 | — | — | |
| SCHEMBL19017774 | 0.80 | — | — | |
| SCHEMBL64698 | 0.80 | — | — | |
| SCHEMBL6805621 | 0.79 | — | — | |
| SCHEMBL12961391 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112302-B1 | CATAPHORETIC ELECTRODEPOSITION OF POLYETHERIMIDE | GEN ELECTRIC (US) | 2003-09-17 | — | — | EP | claimed |
| US-10800771-B2 | Process for the preparation of dasatinib polymorph | NATCO PHARMA LIMITED (IN) | 2020-10-13 | — | — | US | disclosed |
| US-20190292177-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF DASATINIB POLYMORPH | NATCO PHARMA LIMITED (IN) | 2019-09-26 | — | — | US | disclosed |
| US-9714247-B2 | Multiple kinase pathway inhibitors | TOLERO PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170107215-A1 | MULTIPLE KINASE PATHWAY INHIBITORS | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2017-04-20 | — | — | US | disclosed |
| US-9518240-B2 | Process for the treatment of liquefied hydrocarbons using 3-(piperazine-1-YL)propane-1,2-diol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-13 | — | — | US | disclosed |
| US-9493454-B2 | Multiple kinase pathway inhibitors | TOLERO PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2861699-B1 | PROCESS FOR THE TREATMENT OF LIQUEFIED HYDROCARBONS USING 3-(PIPERAZINE-1-YL) PROPANE-1,2-DIOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-10-19 | — | — | EP | disclosed |
| CN-102847414-B | The carbon dioxide recovery system, in accordance of waste gas and method | 现代自动车株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-103080269-B | Photochromic composition | TOKUYAMA CORP. (JP) | 2015-12-16 | — | — | CN | disclosed |
| US-20040024057-A1 | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use related applications | NITROMED, INC. | 2004-02-05 | — | — | US | disclosed |
| EP-0625997-B2 | AMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS | AIR PROD & CHEM (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5686643-A | FOR PRODUCING POLYURETHANES OR POLYUREAS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0625997-B1 | AMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS | AIR PROD & CHEM (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0625997-A1 | DIAMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS. | RWE DEA AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993016124-A1 | DIAMINOCARBONATE COMPOUNDS AND THEIR USE AS CATALYSTS | RWE-DEA Aktiengesellschaft für Mineraloel und Chemie (DE) | 1993-08-19 | — | — | WO | disclosed |
| US-4766125-A | N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-08-23 | — | — | US | disclosed |
| EP-0068544-B1 | NOVEL N-ARYL-PIPERAZINEALKANAMIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-06-03 | — | — | EP | disclosed |
| US-4617418-A | REACTING AMMONIA, A POLYALKYLENEPOLYAMINE AND AN AMINOALKANOL USING A SOLID ACID CATALYST BED | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0068544-A2 | Novel N-aryl-piperazinealkanamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-01-05 | — | — | EP | disclosed |