Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21982015 | 1.00 | MEN1 (0.52) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL19986282 | 1.00 | MEN1 (0.52) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL31206803 | 0.96 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL19971940 | 0.88 | MEN1 (0.61) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL19971939 | 0.88 | MEN1 (0.61) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL19971937 | 0.88 | MEN1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL19971936 | 0.88 | MEN1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL10067547 | 0.87 | MEN1 (0.47) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL30186579 | 0.86 | MEN1 (0.60) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL8602068 | 0.86 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274360-B1 | SOLUTION PHASE METHOD FOR PREPARING ETELCALCETIDE | AMGEN INC (US) | 2020-05-06 | — | — | EP | disclosed |