Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.73 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675690 | 0.90 | ALK (0.74) | ALKKDRINSR | |
| SCHEMBL20004172 | 0.87 | ALK (0.61) | ALKKDRINSRKIT | |
| SCHEMBL7815503 | 0.86 | ALK (0.78) | ALKKDRINSRKIT | |
| SCHEMBL24676762 | 0.85 | ALK (0.75) | ALKKDRINSRKIT | |
| SCHEMBL896899 | 0.84 | ALK (1.00) | ALKKDRINSRKIT | |
| Hydrochloric Acid SCHEMBL30730875 | 0.83 | ALK (0.98) | ALKKDRINSRKIT | |
| Hydrochloric Acid SCHEMBL14990947 | 0.83 | ALK (0.98) | ALKKDRINSRKIT | |
| SCHEMBL20004176 | 0.81 | ALK (0.73) | ALKKDRKIT | |
| SCHEMBL20004735 | 0.80 | ALK (0.77) | ALKKDRINSRKIT | |
| SCHEMBL20366537 | 0.79 | ALK (0.76) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10646468-B2 | Composition comprising tetracyclic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646468-B2 | Composition comprising tetracyclic compound | ALK, ALPI, TTR | ALK 1/4885KDR 71/4885INSR 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.