Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | ADH7 | P40394 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686661 | 0.98 | EPHX1 (0.68) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL24999126 | 0.98 | EPHX1 (0.68) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL21084325 | 0.98 | EPHX1 (0.68) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL25654170 | 0.98 | EPHX1 (0.68) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL26384915 | 0.98 | EPHX1 (0.68) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL18758414 | 0.95 | EPHX1 (0.56) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL27334711 | 0.95 | EPHX1 (0.56) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL19198224 | 0.95 | EPHX1 (0.56) | EPHX1ACE2OPRM1ALDH1A1TSHR | |
| SCHEMBL19427053 | 0.93 | EPHX1 (0.61) | EPHX1ACE2OPRM1TSHRLMNA | |
| SCHEMBL21478008 | 0.91 | EPHX1 (0.50) | EPHX1ACE2OPRM1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650450-B1 | CRYSTAL FORM II OF THIENOPYRIDINE DERIVATIVE BISULFATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | ZHONGRONG KAITE BEIJING BIOTECHNOLOGY CO LTD (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-10980889-B1 | C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors | Revolution Medicines, Inc. (US) | 2021-04-20 | — | — | US | disclosed |
| EP-3650450-A1 | CRYSTAL FORM II OF THIENOPYRIDINE DERIVATIVE BISULFATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | Zhongrong Kaite (Beijing) Biotechnology Co. Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10980889-B1 | C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors | MTOR, RICTOR, RPTOR | EPHX1 4779/4885ACE2 3052/4885OPRM1 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.