Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138300 | 0.92 | TSHR (0.47) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL11910719 | 0.92 | TSHR (0.47) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL17138293 | 0.92 | TSHR (0.47) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL11133430 | 0.92 | TSHR (0.47) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL17138331 | 0.92 | TSHR (0.47) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL8388564 | 0.87 | TSHR (0.53) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL10356297 | 0.87 | TSHR (0.53) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL10356347 | 0.87 | TSHR (0.53) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL19119178 | 0.87 | TSHR (0.53) | TSHRTHRBEPHX1DNM1ALDH1A1 | |
| SCHEMBL10356295 | 0.87 | TSHR (0.53) | TSHRTHRBEPHX1DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392255-B1 | UNSATURATED BOND-CONTAINING BISSILYL COMPOUND AND MAKING METHOD | SHINETSU CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | disclosed |