Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306660 | 0.94 | SOS1 (0.39) | SOS1SOS2KDM4EGAATSHR | |
| SCHEMBL12605188 | 0.89 | KDM4E (0.35) | SOS1SOS2KDM4EGAATSHR | |
| SCHEMBL19286112 | 0.88 | TSHR (0.37) | SOS1SOS2TSHR | |
| SCHEMBL19226440 | 0.83 | SOS1 (0.36) | SOS1SOS2TSHR | |
| SCHEMBL23126208 | 0.79 | SOS1 (0.34) | SOS1SOS2TSHR | |
| SCHEMBL18820446 | 0.79 | KDM4E (0.36) | SOS1SOS2KDM4EKMT2A | |
| SCHEMBL14962053 | 0.78 | SOS1 (0.52) | SOS1SOS2 | |
| SCHEMBL14962054 | 0.78 | — | — | |
| SCHEMBL12314024 | 0.78 | — | — | |
| SCHEMBL1753717 | 0.77 | SOS1 (0.41) | SOS1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |