Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24855104 | 1.00 | HRH3 (0.36) | HRH3PGRKCNH2TP53NSD2 | |
| SCHEMBL10176831 | 1.00 | HRH3 (0.36) | HRH3PGRKCNH2TP53NSD2 | |
| SCHEMBL24317711 | 0.89 | HRH3 (0.36) | HRH3 | |
| SCHEMBL10098676 | 0.88 | HRH3 (0.40) | HRH3TP53 | |
| SCHEMBL8438506 | 0.86 | HRH3 (0.38) | HRH3PGR | |
| SCHEMBL13242282 | 0.85 | — | — | |
| SCHEMBL21371149 | 0.83 | — | — | |
| SCHEMBL20906895 | 0.82 | HRH3 (0.38) | HRH3PGRKCNH2 | |
| SCHEMBL24854806 | 0.82 | HRH3 (0.38) | HRH3PGRKCNH2 | |
| SCHEMBL10176833 | 0.82 | HRH3 (0.38) | HRH3PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |