Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702779 | 1.00 | CRBN (0.63) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL29090079 | 0.86 | CRBN (0.55) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL1161095 | 0.80 | PLD1 (0.56) | CRBNALOX5PLD1CHEK1AURKA | |
| Hydrochloric Acid SCHEMBL1191652 | 0.78 | PLD1 (0.54) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL36363978 | 0.77 | CRBN (1.00) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL30910151 | 0.77 | PIM1 (0.50) | CRBNALOX5PLD1PIM1SMN1; SMN2 | |
| SCHEMBL22612095 | 0.77 | CRBN (1.00) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL26090875 | 0.77 | PIM1 (0.50) | CRBNALOX5PLD1PIM1SMN1; SMN2 | |
| SCHEMBL19913871 | 0.77 | CRBN (0.54) | CRBNALOX5PLD1CHEK1AURKA | |
| SCHEMBL10847778 | 0.76 | MAP3K5 (0.48) | CRBNALOX5SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705284-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | Emory University (US) | 2026-03-11 | — | — | EP | claimed |
| WO-2025235664-A1 | PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2025-11-13 | — | — | WO | claimed |
| WO-2024233354-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2024-11-14 | — | — | WO | claimed |
| US-20060182762-A1 | Enterovirus, vaccines, medicaments and diagnostic kits | AMSTERDAM INSTITUTE OF VIRAL GENOMICS B.V. (NL) | 2006-08-17 | — | — | US | claimed |
| EP-1625214-A1 | NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS | Amsterdam Institute of Viral Genomics B.V. (NL) | 2006-02-15 | — | — | EP | claimed |
| WO-2004104189-A1 | NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS | AMSTERDAM INSTITUTE OF VIRAL GENOMICS B.V. (NL) | 2004-12-02 | — | — | WO | claimed |
| US-20260124226-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | UNIV EMORY (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4705284-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | Emory University (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2025-04-10 | — | — | US | disclosed |
| WO-2024233354-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-116120282-B | Compounds with EV71 and/or CVA16 virus inhibiting activity and application thereof | 苏州系统医学研究所 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| CN-116120282-A | Compounds with EV71 and/or CVA16 virus inhibiting activity and application thereof | 苏州系统医学研究所 | 2023-05-16 | — | — | CN | disclosed |
| EP-0200299-B1 | PYRIDINYLIMIDAZOLIDINONE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0200299-A1 | Pyridinylimidazolidinone compounds | ELI LILLY AND COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0200299-A1 | Pyridinylimidazolidinone compounds | ELI LILLY AND COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0200299-A1 | Pyridinylimidazolidinone compounds | ELI LILLY AND COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4600430-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| US-4600430-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
| US-4600430-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1986-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | CKS1B, CSNK1A1, CKS2 | CRBN 238/4885ALOX5 4773/4885PLD1 1066/4885 |
| US-20060182762-A1 | Enterovirus, vaccines, medicaments and diagnostic kits | CD99, CD63, FAM83B | CRBN 2190/4885ALOX5 4295/4885PLD1 4574/4885 |
| US-20260124226-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | NSUN2, SARS1, SNRPE | CRBN 1358/4885ALOX5 945/4885PLD1 2951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.