Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 13/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22059489 | 0.90 | EPHX2 (0.82) | EPHX2NR1H4PPARG | |
| SCHEMBL22060068 | 0.90 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL22060075 | 0.88 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL28364517 | 0.87 | EPHX2 (0.83) | EPHX2NR1H4PPARG | |
| SCHEMBL22059484 | 0.86 | EPHX2 (0.75) | EPHX2NR1H4PPARG | |
| SCHEMBL22059490 | 0.86 | EPHX2 (0.75) | EPHX2NR1H4PPARG | |
| SCHEMBL22060076 | 0.85 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL21990335 | 0.85 | EPHX2 (0.79) | EPHX2NR1H4PPARG | |
| SCHEMBL20287493 | 0.84 | EPHX2 (0.73) | EPHX2NR1H4PPARG | |
| SCHEMBL29598294 | 0.84 | EPHX2 (0.73) | EPHX2NR1H4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN (DE) | 2020-06-04 | — | — | US | disclosed |
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN (DE) | 2020-06-04 | — | — | US | disclosed |
| CN-110891560-A | Dual modulators of farnesoid X receptor and soluble epoxide hydrolase | 法兰克福大学 | 2020-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | NR1H4, NR1H3, NR1H2 | EPHX2 6/4885NR1H4 1/4885PPARG 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.