Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27046552 | 0.90 | CYP11B1 (0.43) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL12832226 | 0.88 | CYP11B1 (0.46) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL21557329 | 0.88 | CHRM2 (0.42) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL1753879 | 0.86 | CYP11B1 (0.50) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL16189946 | 0.83 | BRD4 (0.41) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL18820444 | 0.78 | TSHR (0.44) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL16189944 | 0.76 | — | — | |
| SCHEMBL23747695 | 0.76 | CYP11B1 (0.36) | CYP11B1CYP11B2CRBNBRD4BRD2 | |
| SCHEMBL3477441 | 0.76 | CYP11B1 (0.40) | CYP11B1CYP11B2CRBNCHRM2CHRM3 | |
| SCHEMBL18820454 | 0.75 | CYP11B1 (0.40) | CYP11B1CYP11B2CRBNCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310084-A1 | PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF | Jinan University (CN) | 2024-01-24 | — | — | EP | disclosed |
| EP-3172214-B1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-05-13 | — | — | EP | disclosed |