Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074667 | 0.77 | — | — | |
| SCHEMBL13177029 | 0.77 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL12261886 | 0.77 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL14346962 | 0.76 | TDP1 (0.53) | TDP1TSHRLMNAL3MBTL1 | |
| SCHEMBL16074668 | 0.76 | TDP1 (0.53) | TDP1TSHRLMNAL3MBTL1 | |
| SCHEMBL22652150 | 0.76 | TDP1 (0.40) | TDP1TSHRLMNAL3MBTL1 | |
| SCHEMBL26317760 | 0.74 | TDP1 (0.38) | TDP1TSHR | |
| SCHEMBL2509779 | 0.74 | TSHR (0.44) | TDP1TSHR | |
| SCHEMBL15889663 | 0.74 | TDP1 (0.50) | TDP1TSHRLMNAL3MBTL1 | |
| SCHEMBL18271003 | 0.74 | TDP1 (0.50) | TDP1TSHRLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200149062-A1 | ENGINEERED TSC2 | THE JOHNS HOPKINS UNIVERSITY | 2020-05-14 | — | — | US | disclosed |