Trifluralin

Trifluralin

SCHEMBL21994

CCCN(CCC)c1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 1.00
CYP3A4 P08684 3/20 1.00
MAPK1 P28482 2/20 1.00
TSHR P16473 2/20 1.00
MAPT P10636 3/20 0.74
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 1/20 0.51
HIF1A Q16665 1/20 0.51
TXNRD1 Q16881 1/20 0.51
TXNRD3 Q86VQ6 1/20 0.51
TXNRD2 Q9NNW7 1/20 0.51
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
PTPN5 P54829 1/20 0.44
ALDH3A1 P30838 1/20 0.43
HCAR3 P49019 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluralin SCHEMBL8409474 1.00 TDP1 (1.00) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11202092 0.94 CYP3A4 (0.89) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11204357 0.94 TDP1 (0.89) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL11810287 0.93 CYP3A4 (0.86) TDP1CYP3A4MAPK1TSHRMAPT
Fluchloralin SCHEMBL54746 0.93 CYP3A4 (0.86) TDP1CYP3A4MAPK1TSHRMAPT
Fluchloralin SCHEMBL8534586 0.93 CYP3A4 (0.86) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL7181566 0.91 MAPT (0.89) TDP1CYP3A4MAPK1TSHRMAPT
SCHEMBL20472302 0.91 TDP1 (0.82) TDP1CYP3A4MAPK1TSHRMAPT
Benfluralin SCHEMBL8522913 0.91 CYP3A4 (0.92) TDP1CYP3A4MAPK1TSHRMAPT
Trifluralin SCHEMBL11058031 0.89 TDP1 (0.80) TDP1CYP3A4MAPK1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 31449 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144260-A1 COMPOSITION AND METHOD FOR IMPROVING AGRONOMIC TRAITS OF A PLANT THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-05-28 US claimed
US-20260137041-A1 SIMULTANEOUS GENE EDITING AND HAPLOID INDUCTION SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-12622925-B2 Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2026-05-12 US claimed
US-20260096553-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2026-04-09 US claimed
US-12593765-B2 Simultaneous gene editing and haploid induction SYNGENTA CROP PROTECTION AG (CH) 2026-04-07 US claimed
EP-4713317-A1 A PROCESS FOR PURIFICATION OF ETHOFUMESATE Adama Agan Ltd. (IL) 2026-03-25 EP claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
CN-121577800-A Non-targeted screening multi-pesticide residue detection method based on high-resolution mass spectrum 常州市食品药品纤维质量监督检验中心(常州市粮油质量监督检测站、常州纤维检验所) 2026-02-27 CN claimed
EP-4691241-A1 METHOD FOR SELECTIVELY CONTROLLING WEEDS BASF SE (DE) 2026-02-11 EP claimed
EP-4307408-B1 POSITIVE ELECTRODE MATERIAL AND PREPARATION METHOD THEREFOR BEIJING EASPRING MAT TECH CO LTD (CN) 2026-01-28 EP claimed
EP-0044209-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-20 EP claimed
US-4277364-A Encapsulation by entrapment THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1981-07-07 US claimed
US-4226789-A Removal of nitrosamines from denitroanilines by treatment with HCl ELI LILLY AND COMPANY (US) 1980-10-07 US claimed
US-4185035-A REMOVAL OF NITROSAMINES WITH PHOSPHORUS HALIDES ELI LILLY AND COMPANY (US) 1980-01-22 US claimed
US-4174960-A HERBICIDES, 2,6-DINITROANILINE DERIVATIVES LILLY INDUSTRIES LIMITED (GB) 1979-11-20 US claimed
US-4156722-A FUNGICIDES, PARASITICIDES ELI LILLY AND COMPANY (US) 1979-05-29 US claimed
US-4127610-A REMOVAL OF NITROSAMINES ELI LILLY AND COMPANY (US) 1978-11-28 US claimed
US-4077795-A 2,4-DINITROANILINE DERIVATIVES UNION CARBIDE CORPORATION (US) 1978-03-07 US claimed
US-4073638-A APPLYING 5-ETHYL-N,N-DIPROPYL THIOCARBAMATE AND N,N-DIPROPYL-4-TRIFLUOROMETHYL-2,6-DINITROANILINE MACMURRAY ROBERT R 1978-02-14 US claimed
US-3967953-A N,N-DIPROPYL-4-TRIFLUOROMETHYL-2,6-DINITROANILINE, 2,4-DICHLOROPHENOXYACETIC ACID OR SALTS AMERICAN AGTECH, INC. (US) 1976-07-06 US claimed