Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 4/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16943519 | 1.00 | KLK7 (0.57) | KLK7GPR119STSFKBP1AYAP1 | |
| SCHEMBL16943520 | 1.00 | KLK7 (0.57) | KLK7GPR119STSFKBP1AYAP1 | |
| SCHEMBL1150828 | 0.90 | KLK7 (0.55) | KLK7GPR119STSMEN1KMT2A | |
| SCHEMBL7698816 | 0.90 | KLK7 (0.55) | KLK7GPR119STSMEN1KMT2A | |
| SCHEMBL16732580 | 0.90 | KLK7 (0.55) | KLK7GPR119STSMEN1KMT2A | |
| SCHEMBL7511892 | 0.90 | KLK7 (0.55) | KLK7GPR119STSMEN1KMT2A | |
| SCHEMBL10035703 | 0.88 | KLK7 (0.53) | KLK7GPR119STSYAP1MEN1 | |
| SCHEMBL24589437 | 0.87 | KLK7 (0.53) | KLK7FKBP1AHTTKLK5NPC1 | |
| SCHEMBL10628988 | 0.86 | KLK7 (0.51) | KLK7GPR119STSFKBP1AKLK5 | |
| SCHEMBL23270771 | 0.86 | HTT (0.45) | KLK7FKBP1AHTTKLK5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113077-A9 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020113077-A1 | COMPOSITIONS AND METHODS FOR MODULAR CONTROL OF BIOORTHOGONAL LIGATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |