Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.54 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22835178 | 0.85 | DDB1 (0.51) | DDB1CRBNIKZF3 | |
| SCHEMBL26351978 | 0.85 | DDB1 (0.51) | DDB1CRBNIKZF3 | |
| SCHEMBL23536487 | 0.85 | DDB1 (0.50) | DDB1CRBNIKZF3 | |
| SCHEMBL23536488 | 0.84 | DDB1 (0.49) | DDB1CRBNIKZF3 | |
| SCHEMBL23572280 | 0.84 | DDB1 (0.49) | DDB1CRBNIKZF3 | |
| SCHEMBL23536472 | 0.83 | DDB1 (0.48) | DDB1CRBNIKZF3 | |
| SCHEMBL23572115 | 0.83 | DDB1 (0.48) | DDB1CRBNIKZF3 | |
| SCHEMBL30627204 | 0.82 | DDB1 (0.66) | DDB1CRBNIKZF3 | |
| SCHEMBL25972262 | 0.82 | DDB1 (0.66) | DDB1CRBNIKZF3 | |
| SCHEMBL23536389 | 0.82 | DDB1 (0.57) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113233-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |