Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998481 | 0.86 | CYP3A4 (0.49) | CYP3A4ATMKDM4EALDH1A1CYP19A1 | |
| SCHEMBL21998482 | 0.84 | HPGD (0.56) | CYP3A4ATMGABRA1GABRB2KDM4E | |
| SCHEMBL21933257 | 0.83 | EPHX2 (0.55) | CYP3A4ATMGABRA1GABRB2KDM4E | |
| SCHEMBL21998484 | 0.81 | CYP19A1 (0.44) | CYP3A4ATMKDM4EALDH1A1CYP19A1 | |
| SCHEMBL21998729 | 0.80 | HPGD (0.56) | CYP3A4ALDH1A1CYP19A1POLBMAPT | |
| SCHEMBL21994187 | 0.80 | MEN1 (0.52) | CYP3A4GABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL21933265 | 0.77 | MAPT (0.59) | CYP3A4ATMKDM4EALDH1A1EPHX2 | |
| SCHEMBL21998480 | 0.74 | EPHX2 (0.70) | CYP3A4ATMKDM4EALDH1A1EPHX2 | |
| SCHEMBL21998502 | 0.72 | MAPT (0.49) | CYP3A4KDM4EALDH1A1EPHX2TRPV1 | |
| SCHEMBL13678088 | 0.72 | MAPT (0.65) | ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | CYP3A4 1011/4885ATM 1371/4885GABRA1 1666/4885 |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | STS, F12, STK38L | CYP3A4 1376/4885ATM 1255/4885GABRA1 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.