Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999188 | 0.93 | DDR1 (0.33) | DDR1CNR1TYK2 | |
| SCHEMBL21999338 | 0.90 | SCN9A (0.34) | DDR1IRAK4SCN9AALDH1A1 | |
| SCHEMBL21796211 | 0.86 | DDR1 (0.38) | DDR1CNR1 | |
| SCHEMBL21999189 | 0.86 | F10 (0.36) | IRAK4SCN9ASCN7AKCNH2SCN5A | |
| SCHEMBL18498639 | 0.84 | DDR1 (0.39) | DDR1IRAK4SCN9A | |
| SCHEMBL21998970 | 0.83 | PTPN1 (0.32) | SCN9A | |
| SCHEMBL21999184 | 0.81 | DDR1 (0.37) | DDR1IRAK4SCN9ASCN7AKCNH2 | |
| SCHEMBL18506249 | 0.81 | DDR1 (0.35) | DDR1ALDH1A1HSD17B10 | |
| SCHEMBL21999183 | 0.79 | MAPK14 (0.34) | SCN9ASCN7AKCNH2SCN5ATYK2 | |
| SCHEMBL21999358 | 0.79 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-17 | — | — | US | disclosed |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11089783-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | AHR, DDT, CYP8B1 | DDR1 2201/4885IRAK4 3604/4885SCN9A 2083/4885 |
| US-20200146293-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES | AHR, DDT, CYP8B1 | DDR1 2201/4885IRAK4 3604/4885SCN9A 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.