SCHEMBL2200140

SCHEMBL2200140

O=S(=O)(O)c1cc(Nc2nc(Cl)nc(Nc3ccccc3)n2)ccc1C=Cc1ccc(Nc2nc(Cl)nc(Nc3ccccc3)n2)cc1S(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.54
CA1 P00915 5/20 0.54
CA2 P00918 5/20 0.54
CA9 Q16790 5/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
NFKB1 P19838 1/20 0.50
CHAT P28329 3/20 0.48
USP2 O75604 1/20 0.48
APEX1 P27695 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
LMNA P02545 1/20 0.48
ENPP3 O14638 1/20 0.47
ENPP1 P22413 1/20 0.47
HPGDS O60760 1/20 0.46
P2RX7 Q99572 1/20 0.44
P2RX2 Q9UBL9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11599622 1.00 CA12 (0.54) CA12CA1CA2CA9MEN1
SCHEMBL11879462 0.99 CA12 (0.53) CA12CA1CA2CA9MEN1
SCHEMBL1536252 0.99 CA12 (0.53) CA12CA1CA2CA9MEN1
SCHEMBL1536256 0.99 CA12 (0.56) CA12CA1CA2CA9MEN1
Potassium SCHEMBL2203007 0.99 CA12 (0.53) CA12CA1CA2CA9MEN1
SCHEMBL2222015 0.98 CA12 (0.52) CA12CA1CA2CA9MEN1
Potassium SCHEMBL2203859 0.98 CA12 (0.55) CA12CA1CA2CA9MEN1
SCHEMBL15893991 0.95 CA12 (0.50) CA12CA1CA2CA9MEN1
SCHEMBL17550070 0.95 CA12 (0.50) CA12CA1CA2CA9MEN1
SCHEMBL17550065 0.94 CA12 (0.52) CA12CA1CA2CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2716466-B1 THERMAL RECORDING MATERIAL CONTAINING STILBENE DISULPHONIC ACID FLUORESCENT WHITENING AGENT RICOH IND FRANCE SAS (FR) 2016-09-14 EP disclosed
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 EP disclosed
EP-2222652-B1 STORAGE STABLE SOLUTIONS OF OPTICAL BRIGHTENERS CLARIANT FINANCE BVI LTD (VG) 2015-09-30 EP disclosed
US-8894815-B2 Storage stable solutions of optical brighteners CLARIANT FINANCE (BVI) LIMITED (VG) 2014-11-25 US disclosed
US-8784612-B2 2014-07-22 US disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 EP disclosed
US-8546300-B2 Thermosensitive recording material and image recording method RICOH COMPANY, LTD. (JP) 2013-10-01 US disclosed
EP-2345541-B1 Thermosensitive recording material and image recording method RICOH CO LTD (JP) 2012-08-29 EP disclosed
US-20110177941-A1 THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2011-07-21 US disclosed
EP-2345541-A2 Thermosensitive recording material and image recording method Ricoh Company, Ltd. (JP) 2011-07-20 EP disclosed
EP-1511901-B1 WHITENING PIGMENTS CIBA SC HOLDING AG (CH) 2007-07-04 EP disclosed
EP-1752453-A1 Storage stable solutions of optical brighteners Clariant International Ltd. (CH) 2007-02-14 EP disclosed
EP-1511901-A1 WHITENING PIGMENTS Ciba SC Holding AG (CH) 2005-03-09 EP disclosed
WO-2003104560-A1 WHITENING PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-18 WO disclosed
US-4092243-A CONTAINING TRIAZINE RINGS, SELECTIVE ABSORPTION OF HYDROCARBONS BAYER AKTIENGESELLSCHAFT (DT) 1978-05-30 US disclosed
US-4005026-A Detergent compositions containing novel crystalline forms of optical brighteners STERLING DRUG INC. (US) 1977-01-25 US disclosed
US-3957728-A MODIFIED WITH S-TRIAZINES; ABSORBENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed