Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200345 | 1.00 | TYR (0.66) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL1603891 | 0.87 | CHRNA7 (0.67) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL1937971 | 0.85 | MAPT (0.60) | TYRKMT2ACYP3A4RAB9AMAPT | |
| SCHEMBL1937970 | 0.85 | MAPT (0.60) | TYRKMT2ACYP3A4RAB9AMAPT | |
| SCHEMBL28068232 | 0.83 | KMT2A (0.56) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL28068229 | 0.83 | KMT2A (0.56) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL7922934 | 0.80 | CYP3A4 (0.71) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL7922932 | 0.80 | CYP3A4 (0.71) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL1110685 | 0.79 | MAPT (0.62) | TYRKMT2ACYP3A4HSPD1HSPE1 | |
| SCHEMBL31682971 | 0.79 | MAPT (0.62) | TYRKMT2ACYP3A4HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085218-B | A kind of A ring has the quinoid chalcone compound of methyl, preparation method and anti-inflammatory activity | 中国医学科学院药物研究所 | 2019-04-09 | — | — | CN | claimed |
| CN-105085218-A | Quinoid chalcone compound with methyl group at A ring, and preparation method and anti-inflammatory activity thereof | INST MATERIA MEDICA CAMS | 2015-11-25 | — | — | CN | claimed |
| EP-1395539-B1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | ARBONOVA AB OY (FI) | 2009-04-22 | — | — | EP | claimed |
| US-20040199032-A1 | Method for isolating phenolic substances or javabiones from wood comprising knotwood | HOLMBOM BJARNE (FI) | 2004-10-07 | — | — | US | claimed |
| EP-1395539-A1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | Holmbom, Bjarne (FI) | 2004-03-10 | — | — | EP | claimed |
| WO-2002098830-A1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | HOLMBOM BJARNE (FI) | 2002-12-12 | — | — | WO | claimed |
| JP-8113521-A | — | — | None | — | — | JP | disclosed |
| CN-105085218-B | A kind of A ring has the quinoid chalcone compound of methyl, preparation method and anti-inflammatory activity | 中国医学科学院药物研究所 | 2019-04-09 | — | — | CN | disclosed |
| CN-105085218-B | A kind of A ring has the quinoid chalcone compound of methyl, preparation method and anti-inflammatory activity | 中国医学科学院药物研究所 | 2019-04-09 | — | — | CN | disclosed |
| CN-105085218-A | Quinoid chalcone compound with methyl group at A ring, and preparation method and anti-inflammatory activity thereof | INST MATERIA MEDICA CAMS | 2015-11-25 | — | — | CN | disclosed |
| US-7976877-B2 | extracting knotwood with polar solvent and recovering extract, as antioxidative agent; in elastomers, plastics, petrols, bio-oils; for stabilization of lubricants, adhesives, in food, in cosmetics, packing, paints and dispersions; as biocides, especially fungicides, bactericides or insecticides | OY ARBONOVA AB (FI) | 2011-07-12 | — | — | US | disclosed |
| EP-1682631-B1 | USE OF KNOTWOOD EXTRACTS | ARBONOVA AB OY (FI) | 2010-09-08 | — | — | EP | disclosed |
| EP-1395539-B1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | ARBONOVA AB OY (FI) | 2009-04-22 | — | — | EP | disclosed |
| EP-1682631-A1 | USE OF KNOTWOOD EXTRACTS | Oy Arbonova AB (FI) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005047423-A1 | USE OF KNOTWOOD EXTRACTS | OY ARBONOVA AB (FI) | 2005-05-26 | — | — | WO | disclosed |
| US-20040199032-A1 | Method for isolating phenolic substances or javabiones from wood comprising knotwood | HOLMBOM BJARNE (FI) | 2004-10-07 | — | — | US | disclosed |
| EP-1395539-A1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | Holmbom, Bjarne (FI) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002098830-A1 | A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD | HOLMBOM BJARNE (FI) | 2002-12-12 | — | — | WO | disclosed |
| JP-H08113521-A | 2,4,6-TRIHYDROXYCHALCONE AND COSMETIC CONTAINING THE SAME | POLA CHEM IND INC | 1996-05-07 | — | — | JP | disclosed |
| EP-0257887-A2 | Ophthalmic compositions | HOUSTON BIOTECHNOLOGY INCORPORATED (US) | 1988-03-02 | — | — | EP | disclosed |