Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 20/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 20/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535303 | 0.88 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21535296 | 0.86 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21535347 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21535114 | 0.83 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL31259958 | 0.82 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL14789909 | 0.82 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21535348 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21535349 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL21518700 | 0.78 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL14778695 | 0.78 | CYP11B1 (0.69) | CYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-A1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2020-05-20 | — | — | EP | disclosed |