⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285773 | 0.82 | KDM7A (0.32) | — | |
| SCHEMBL24176384 | 0.82 | CACNA2D1 (0.30) | — | |
| Negamycin SCHEMBL564074 | 0.82 | GABRR1 (0.38) | — | |
| Negamycin SCHEMBL21578042 | 0.82 | GABRR1 (0.38) | — | |
| SCHEMBL25466927 | 0.82 | CACNA2D1 (0.30) | — | |
| Negamycin SCHEMBL1650147 | 0.82 | GABRR1 (0.38) | — | |
| SCHEMBL11739232 | 0.77 | CACNA2D1 (0.41) | — | |
| SCHEMBL16279002 | 0.77 | GABRR1 (0.32) | — | |
| SCHEMBL16279005 | 0.77 | GABRR1 (0.32) | — | |
| SCHEMBL21577991 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654135-B2 | Methods for treating colon cancer with compositions comprising amlexanox and immune checkpoint inhibitors | MOONSHOT PHARMA LLC (US) | 2023-05-23 | — | — | US | disclosed |
| US-11135221-B2 | Methods for inducing an immune response | MOONSHOT PHARMA LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-20200155519-A1 | METHODS FOR TREATING CANCER WITH COMPOSITIONS COMPRISING AMLEXANOX AND IMMUNE MODULATORS | MOONSHOT PHARMA LLC (US) | 2020-05-21 | — | — | US | disclosed |