⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234252 | 0.92 | ATM (0.33) | — | |
| SCHEMBL22151778 | 0.90 | — | — | |
| SCHEMBL22005993 | 0.90 | — | — | |
| SCHEMBL20128814 | 0.90 | — | — | |
| SCHEMBL20325435 | 0.90 | — | — | |
| SCHEMBL21906902 | 0.89 | — | — | |
| SCHEMBL20128817 | 0.89 | — | — | |
| SCHEMBL21421656 | 0.84 | — | — | |
| SCHEMBL18592213 | 0.83 | GBA2 (0.38) | — | |
| SCHEMBL24761934 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155690-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. | 2020-05-21 | — | — | US | disclosed |