⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875184 | 0.84 | HCAR2 (0.72) | — | |
| SCHEMBL2629428 | 0.82 | — | — | |
| SCHEMBL4420054 | 0.80 | — | — | |
| SCHEMBL2629429 | 0.80 | — | — | |
| SCHEMBL3760634 | 0.80 | — | — | |
| SCHEMBL2619220 | 0.77 | DAO (0.62) | — | |
| SCHEMBL18680080 | 0.77 | HCAR2 (0.62) | — | |
| SCHEMBL3624738 | 0.77 | MAPK1 (0.67) | — | |
| SCHEMBL8568630 | 0.77 | HCAR2 (0.62) | — | |
| SCHEMBL3954952 | 0.77 | HCAR2 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| EP-3601284-B1 | NAPHTHYRIDINES AS INHIBITORS OF HPK1 | HOFFMANN LA ROCHE (CH) | 2023-12-27 | — | — | EP | claimed |
| US-20230263772-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM INC (US) | 2023-08-24 | — | — | US | claimed |
| EP-4136072-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | Neumentum, Inc. (US) | 2023-02-22 | — | — | EP | claimed |
| CN-113993846-A | Compositions and methods for treating pain and/or inflammation | 诺门图姆股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| US-20220008390-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. | 2022-01-13 | — | — | US | claimed |
| WO-2021211681-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN AND/OR INFLAMMATION | NEUMENTUM, INC. (US) | 2021-10-21 | — | — | WO | claimed |
| EP-2988321-B1 | CLEANING LIQUID COMPOSITION | KANTO KAGAKU (JP) | 2019-03-20 | — | — | EP | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| WO-2006108489-A1 | AMINOPYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-10-19 | — | — | WO | claimed |
| WO-2005084663-A1 | HETERO-SUBSTITUTED ACETANILIDE DERIVATES AS ANALGESIC AGENTS | JANSSEN PHARMACEUTICA N.V. (US) | 2005-09-15 | — | — | WO | claimed |
| US-20050182108-A1 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-18 | — | — | US | claimed |
| US-20050171346-A1 | Hexahydropyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and methods of preparation | AVENTIS PHARMA S.A. (FR) | 2005-08-04 | — | — | US | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| US-20050004178-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | US | claimed |
| US-20040142377-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2004-07-22 | — | — | US | claimed |
| US-20040097482-A1 | Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications | SCHERING CORPORATION | 2004-05-20 | — | — | US | claimed |
| EP-0749448-B1 | USE OF PYRAZOLE-BLOCKED POLYISOCYANATES IN ONE-COMPONENT CLEAR COATINGS | ARCO CHEM TECH (US) | 2001-05-30 | — | — | EP | claimed |