Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31684271 | 0.89 | BTK (0.49) | BTK | |
| SCHEMBL21903689 | 0.89 | BTK (0.49) | BTK | |
| SCHEMBL21965766 | 0.89 | BTK (0.49) | BTK | |
| SCHEMBL21903643 | 0.85 | BTK (0.46) | BTKOPRK1 | |
| SCHEMBL31684327 | 0.81 | BTK (0.44) | BTK | |
| SCHEMBL21965243 | 0.81 | BTK (0.44) | BTK | |
| SCHEMBL21903785 | 0.81 | BTK (0.52) | BTK | |
| SCHEMBL21903789 | 0.81 | BTK (0.52) | BTK | |
| SCHEMBL21903812 | 0.80 | BTK (0.41) | BTK | |
| SCHEMBL21903675 | 0.80 | BTK (0.45) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-A1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-05-20 | — | — | EP | disclosed |