Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486598 | 0.78 | CA12 (0.30) | CA12CA9CA2 | |
| SCHEMBL20472243 | 0.75 | CA12 (0.43) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL6891210 | 0.75 | CA12 (0.43) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL375752 | 0.75 | CA12 (0.43) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL1931283 | 0.72 | CA12 (0.40) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL19864387 | 0.72 | CA12 (0.40) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL9456154 | 0.70 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL20472201 | 0.70 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL7723650 | 0.69 | DPP4 (0.34) | HTR1ALMNA | |
| SCHEMBL13332903 | 0.69 | CA12 (0.44) | CA12CA9CA2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098658-A1 | 20-SUBSTITUTED CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国海洋大学 | 2020-05-22 | — | — | WO | disclosed |