Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18259388 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259390 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259389 | 1.00 | USP2 (0.39) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL29318676 | 0.89 | USP2 (0.41) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259633 | 0.81 | USP2 (0.47) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259632 | 0.81 | USP2 (0.47) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259631 | 0.81 | USP2 (0.43) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259311 | 0.81 | USP2 (0.43) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18259310 | 0.81 | USP2 (0.43) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL23877994 | 0.80 | USP2 (0.50) | USP2SMN1; SMN2RECQLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122747-B1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | NORTH & SOUTH BROTHER PHARMACY INVESTMENT CO LTD (CN) | 2020-05-20 | — | — | EP | disclosed |