Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22011056 | 0.76 | MAPT (0.32) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22011054 | 0.76 | MAPT (0.32) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22010472 | 0.75 | LRRK2 (0.31) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22518949 | 0.75 | KMT2A (0.35) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL21983696 | 0.74 | APEX1 (0.38) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22011506 | 0.73 | — | — | |
| SCHEMBL858032 | 0.72 | SLC22A12 (0.43) | MAPTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23963815 | 0.70 | AURKA (0.32) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15004370 | 0.69 | ERN1 (0.36) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22010500 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |