SCHEMBL22011527

SCHEMBL22011527

CNc1ncc(/C=C/C(=O)N(C)Cc2oc3cccc(N)c3c2C)cc1NC[C@H](O)C=O

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.30
MEF2D Q14814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011030 0.89 HDAC4 (0.31) HDAC4MEF2D
SCHEMBL22010532 0.89
SCHEMBL22011058 0.89
SCHEMBL22011519 0.84
SCHEMBL22011510 0.81 HDAC4 (0.30) HDAC4MEF2D
SCHEMBL22011505 0.80 PLAU (0.31)
SCHEMBL13813400 0.78
SCHEMBL22010782 0.75
SCHEMBL24722668 0.74
SCHEMBL22010781 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099341-A1 ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF DEBIOPHARM INTERNATIONAL S.A. (CH) 2020-05-22 WO disclosed