Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24995746 | 0.79 | PIK3CD (0.48) | PIK3CDCYP2D6SMN1; SMN2 | |
| SCHEMBL18926695 | 0.75 | PIK3CD (0.58) | PIK3CDCYP2D6SMN1; SMN2 | |
| SCHEMBL18505950 | 0.73 | ATM (0.40) | — | |
| SCHEMBL16941607 | 0.73 | — | — | |
| SCHEMBL11998897 | 0.70 | PIK3CD (0.38) | PIK3CDCYP2D6SMN1; SMN2 | |
| SCHEMBL10446321 | 0.70 | — | — | |
| SCHEMBL23740711 | 0.70 | PIK3CD (0.54) | PIK3CDCYP2D6SMN1; SMN2 | |
| SCHEMBL19362302 | 0.70 | PIK3CD (0.48) | PIK3CD | |
| SCHEMBL24841690 | 0.70 | PIK3CD (0.48) | PIK3CD | |
| SCHEMBL12369900 | 0.70 | PIK3CD (0.40) | PIK3CDCYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016105-A1 | BIASED NMDA RECEPTOR MODULATORS AND USES THEREOF | EDWARD Via COLLEGE OF OSTEOPATHIC MEDICINE | 2022-01-20 | — | — | US | disclosed |
| WO-2020102443-A1 | BIASED NMDA RECEPTOR MODULATORS AND USES THEREOF | EDWARD Via COLLEGE OF OSTEOPATHIC MEDICINE (US) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016105-A1 | BIASED NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | PIK3CD 2262/4885CYP2D6 3722/4885SMN1; SMN2 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.