SCHEMBL22012376

SCHEMBL22012376

Cc1cc(C(C)(C)c2ccc(OC(=O)Oc3ccc(C(C)(C)c4ccc(O)c(C)c4)cc3C)c(C)c2)ccc1O

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.65
ESR2 Q92731 3/20 0.44
AR P10275 2/20 0.43
KLF10 Q13118 1/20 0.41
ESRRG P62508 1/20 0.40
VDR P11473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22012374 0.90 ESR1 (0.53) ESR1ESR2ARVDR
SCHEMBL11949465 0.90 ESR1 (0.53) ESR1ESR2AR
SCHEMBL22012375 0.90 ESR1 (0.53) ESR1ESR2ARVDR
SCHEMBL5034647 0.89 ESR1 (0.62) ESR1ESR2ARKLF10
SCHEMBL5146787 0.88 ESR1 (0.61) ESR1ESR2ARKLF10ESRRG
SCHEMBL26559684 0.85 ESR1 (0.57) ESR1ESR2ARKLF10ESRRG
SCHEMBL19647441 0.85 ESR1 (0.57) ESR1ESR2ARKLF10
SCHEMBL12949862 0.84 ESR1 (0.56) ESR1ESR2ARKLF10ESRRG
SCHEMBL16395116 0.83 ESR1 (0.44) ESR1ARVDR
SCHEMBL16784755 0.83 ESR1 (0.54) ESR1ESR2ESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3388466-B1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL IND (JP) 2022-03-23 EP disclosed
US-10662286-B2 Aromatic polycarbonate oligomer solid Honchu Chemical Industry Co., Ltd. (JP) 2020-05-26 US disclosed