Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497525 | 1.00 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22204208 | 0.87 | PIK3CG (0.65) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22204206 | 0.87 | PIK3CG (0.65) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL29314052 | 0.86 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22204280 | 0.84 | PIK3CG (0.53) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL21929874 | 0.84 | PIK3CG (0.53) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL21929873 | 0.84 | PIK3CG (0.53) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22768638 | 0.84 | PIK3CG (0.61) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22204279 | 0.84 | PIK3CG (0.53) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22011787 | 0.84 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102198-A1 | HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020102216-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2020-05-22 | — | — | WO | disclosed |