Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586670 | 0.92 | NTRK1 (0.48) | NTRK1NTRK3JAK2 | |
| SCHEMBL29692857 | 0.92 | NTRK1 (0.48) | NTRK1NTRK3JAK2 | |
| SCHEMBL22013110 | 0.92 | NTRK1 (0.48) | NTRK1NTRK3JAK2 | |
| SCHEMBL22013109 | 0.90 | NTRK1 (0.43) | NTRK1NTRK3 | |
| SCHEMBL22013095 | 0.89 | NTRK1 (0.41) | NTRK1NTRK3JAK2 | |
| SCHEMBL23825254 | 0.88 | NTRK1 (0.43) | NTRK1NTRK3JAK2 | |
| SCHEMBL23825255 | 0.87 | NTRK1 (0.40) | NTRK1NTRK3JAK2 | |
| SCHEMBL23825270 | 0.83 | NTRK1 (0.48) | NTRK1NTRK3JAK2 | |
| SCHEMBL23837027 | 0.83 | NTRK1 (0.40) | NTRK1NTRK3JAK2 | |
| SCHEMBL22013270 | 0.83 | NTRK1 (0.40) | NTRK1NTRK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098723-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |