Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADM2 | Q7Z4H4 | 10/20 | 0.61 |
| ▸ | CALCB | P10092 | 9/20 | 0.61 |
| ▸ | CALCRL | Q16602 | 10/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368768 | 0.87 | ADM2 (0.60) | ADM2CALCBCALCRL | |
| SCHEMBL846246 | 0.86 | ADM2 (0.63) | ADM2CALCBCALCRL | |
| SCHEMBL5955987 | 0.86 | ADM2 (0.64) | ADM2CALCBCALCRL | |
| SCHEMBL22010668 | 0.86 | ADM2 (0.66) | ADM2CALCB | |
| SCHEMBL22010416 | 0.86 | ADM2 (0.66) | ADM2CALCB | |
| SCHEMBL31039456 | 0.86 | ADM2 (0.66) | ADM2CALCB | |
| Hydrochloric Acid SCHEMBL20565071 | 0.85 | ADM2 (0.63) | ADM2CALCBCALCRL | |
| Hydrochloric Acid SCHEMBL31039474 | 0.85 | ADM2 (0.63) | ADM2CALCBCALCRL | |
| SCHEMBL22014289 | 0.85 | ADM2 (0.71) | ADM2CALCBCALCRL | |
| SCHEMBL31039432 | 0.84 | ADM2 (0.61) | ADM2CALCBCALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099885-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-05-22 | — | — | WO | disclosed |