Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365306 | 1.00 | ADM2 (0.48) | ADM2CALCB | |
| SCHEMBL29367768 | 0.92 | ADM2 (0.47) | ADM2CALCB | |
| SCHEMBL30203205 | 0.88 | ADM2 (0.54) | ADM2CALCB | |
| SCHEMBL22014517 | 0.88 | ADM2 (0.54) | ADM2CALCB | |
| SCHEMBL21963868 | 0.85 | ADM2 (0.57) | ADM2CALCB | |
| SCHEMBL22014280 | 0.82 | ADM2 (0.59) | ADM2CALCB | |
| SCHEMBL29367816 | 0.81 | ADM2 (0.56) | ADM2CALCB | |
| SCHEMBL22014303 | 0.80 | ADM2 (0.59) | ADM2CALCB | |
| SCHEMBL29365924 | 0.80 | ADM2 (0.59) | ADM2CALCB | |
| SCHEMBL22014033 | 0.80 | ADM2 (0.53) | ADM2CALCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099885-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-05-22 | — | — | WO | disclosed |