Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.89 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.72 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.72 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.72 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefaloram SCHEMBL10428695 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL612837 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL11057775 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL612836 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL11057780 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL27274373 | 0.94 | TDP1 (1.00) | TDP1CTDSP1MAPTNR1I2HPGD | |
| Cefaloram SCHEMBL8722133 | 0.94 | TDP1 (0.98) | TDP1CTDSP1MAPTNR1I2HPGD | |
| SCHEMBL11566566 | 0.92 | TDP1 (0.87) | TDP1CTDSP1MAPTNR1I2HPGD | |
| SCHEMBL11566449 | 0.91 | TDP1 (0.86) | TDP1CTDSP1MAPTNR1I2HPGD | |
| SCHEMBL12318184 | 0.90 | TDP1 (0.84) | TDP1CTDSP1MAPTNR1I2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |