Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 16/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015969 | 0.79 | SSTR4 (0.54) | SSTR4SSTR1SSTR3KDM4ENPC1 | |
| SCHEMBL16255895 | 0.77 | SSTR4 (0.48) | SSTR4SSTR1SSTR3SMN1; SMN2KDM4E | |
| SCHEMBL31740381 | 0.69 | SSTR4 (0.45) | SSTR4SSTR1SSTR3 | |
| SCHEMBL19724715 | 0.69 | SSTR4 (1.00) | SSTR4SSTR1SSTR3 | |
| SCHEMBL16252720 | 0.69 | SSTR4 (1.00) | SSTR4SSTR1SSTR3 | |
| SCHEMBL19724493 | 0.67 | SSTR4 (0.69) | SSTR4SSTR1SSTR3 | |
| SCHEMBL16255917 | 0.67 | SSTR4 (0.69) | SSTR4SSTR1SSTR3 | |
| SCHEMBL31741028 | 0.66 | SSTR4 (0.72) | SSTR4SSTR1SSTR3 | |
| SCHEMBL17763047 | 0.66 | SSTR4 (0.89) | SSTR4SSTR1SSTR3 | |
| SCHEMBL25231489 | 0.66 | SSTR4 (0.52) | SSTR4SSTR1SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |