SCHEMBL22015532

SCHEMBL22015532

CCCCCCCCCCCCN(CCCCC1NC(=O)C(CCCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)NC1=O)CC(O)CCCCCCCCCC

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 1/20 0.40
GPR84 Q9NQS5 5/20 0.35
KDM4E B2RXH2 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
FFAR1 O14842 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TBXA2R P21731 1/20 0.33
PTGFR P43088 1/20 0.33
PTGER2 P43116 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM5A P29375 2/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM4C Q9H3R0 1/20 0.32
PLA2G1B P04054 1/20 0.32
PLA2G2A P14555 1/20 0.32
TRPA1 O75762 2/20 0.32
NR4A2 P43354 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21095785 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL17382235 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL17382618 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21095455 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21095331 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21095192 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21095225 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21095236 1.00 DAGLA (0.40) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL24135093 0.99 DAGLA (0.41) DAGLAGPR84KDM4EFFAR4FFAR1
SCHEMBL21066291 0.99 DAGLA (0.41) DAGLAGPR84KDM4EFFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020102172-A2 METHODS FOR INDUCING IMMUNE TOLERANCE TRANSLATE BIO, INC. (US) 2020-05-22 WO disclosed