Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 17/20 | 0.63 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19564973 | 0.77 | SSTR4 (1.00) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763129 | 0.77 | SSTR4 (1.00) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763126 | 0.77 | SSTR4 (1.00) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL17763125 | 0.71 | SSTR4 (1.00) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015982 | 0.70 | SSTR4 (0.65) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015385 | 0.69 | SSTR4 (0.66) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22015981 | 0.66 | SSTR4 (0.67) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL19724888 | 0.66 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL16252655 | 0.66 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL24048343 | 0.65 | SSTR4 (0.72) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |