SCHEMBL22017056

SCHEMBL22017056

CN[C@H](C(=O)N[C@@H](C)C(=O)C(C)(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PSENEN Q9NZ42 1/20 0.34
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20996961 1.00 PSENEN (0.34) PSENENCTSSCTSKDPP4
SCHEMBL22692391 0.83 PSENEN (0.34) PSENENCTSSCTSK
SCHEMBL18811839 0.83 PSENEN (0.36) PSENENCTSSCTSK
SCHEMBL23682495 0.83 PSENEN (0.36) PSENENCTSSCTSK
SCHEMBL18812406 0.83 PSENEN (0.34) PSENENCTSSCTSK
SCHEMBL22139575 0.80 PSENEN (0.38) PSENENCTSSCTSK
SCHEMBL24015645 0.80 PSENEN (0.33) PSENEN
SCHEMBL24454098 0.80 PSENEN (0.33) PSENEN
SCHEMBL13759903 0.79 DPP4 (0.32) DPP4
SCHEMBL17664752 0.79 DPP4 (0.32) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529422-B2 Polymer linkers and their uses NOVACYTE THERAPEUTICS COMPANY., LTD (CN) 2022-12-20 US disclosed
US-20200155693-A1 POLYMER LINKERS AND THEIR USES NOVACYTE, INC. (US) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529422-B2 Polymer linkers and their uses PHF2, PHF8, PAICS PSENEN 2225/4885CTSS 3881/4885CTSK 4134/4885
US-20200155693-A1 POLYMER LINKERS AND THEIR USES PHF2, PHF8, PAICS PSENEN 2225/4885CTSS 3881/4885CTSK 4134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.