Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 15/20 | 0.62 |
| ▸ | KIT | P10721 | 4/20 | 0.61 |
| ▸ | EGFR | P00533 | 13/20 | 0.59 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017247 | 0.89 | BRAF (0.62) | BRAFKITEGFRCSF1R | |
| SCHEMBL22017245 | 0.86 | KIT (0.65) | BRAFKITEGFR | |
| SCHEMBL22018088 | 0.83 | TMPRSS2 (0.61) | BRAFKITEGFR | |
| SCHEMBL22017772 | 0.81 | BRAF (0.64) | BRAFKITEGFR | |
| SCHEMBL22024678 | 0.80 | BRAF (0.81) | BRAFKITEGFRCSF1R | |
| SCHEMBL23048203 | 0.79 | KIT (0.76) | BRAFKITEGFRCSF1R | |
| SCHEMBL19500739 | 0.79 | KIT (0.78) | BRAFKITEGFR | |
| SCHEMBL22024682 | 0.79 | BRAF (0.82) | BRAFKITEGFRCSF1R | |
| SCHEMBL12871531 | 0.78 | KIT (0.84) | BRAFKITEGFR | |
| SCHEMBL14318406 | 0.78 | KIT (0.77) | BRAFKITEGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |