Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832303 | 0.88 | POLB (0.80) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13832292 | 0.85 | POLB (0.76) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13831406 | 0.77 | POLB (0.86) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13832282 | 0.77 | POLB (0.79) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15986592 | 0.77 | POLB (0.82) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13832280 | 0.77 | POLB (0.64) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15986441 | 0.76 | POLB (0.83) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13832309 | 0.76 | POLB (0.83) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13831430 | 0.75 | POLB (0.82) | POLBHSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4198470 | 0.75 | MAPT (0.69) | POLBHSD17B10KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |