Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963232 | 0.89 | USP2 (0.49) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22021558 | 0.88 | USP2 (0.48) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL25841931 | 0.86 | USP2 (0.40) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22020099 | 0.80 | SMN1; SMN2 (0.41) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22019806 | 0.79 | GAA (0.59) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22021484 | 0.78 | GAA (0.40) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL30162495 | 0.78 | GAA (0.40) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22020629 | 0.77 | NPSR1 (0.51) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL22020039 | 0.77 | GAA (0.48) | USP2GAACYP1A2NPSR1KDM4E | |
| SCHEMBL24978485 | 0.76 | GAA (0.42) | USP2GAACYP1A2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20160248025-A1 | Organic Electroluminescent Device | UDC IRELAND LTD (IE) | 2016-08-25 | — | — | US | disclosed |