Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17111000 | 0.84 | CA1 (0.31) | CA1CA2CA9CA7 | |
| SCHEMBL6281116 | 0.81 | CA1 (0.41) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL8518064 | 0.79 | CA1 (0.46) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL9715706 | 0.77 | — | — | |
| SCHEMBL733880 | 0.77 | — | — | |
| SCHEMBL827408 | 0.77 | CA1 (0.45) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL16361587 | 0.77 | CA1 (0.45) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL24220212 | 0.76 | CA1 (0.43) | CA1CA2CA9CA7MEN1 | |
| SCHEMBL176303 | 0.76 | — | — | |
| SCHEMBL31756334 | 0.76 | CA1 (0.43) | CA1CA2CA9CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524849-B2 | Hydrophilic organofunctional silicone copolymers | WACKER CHEMIE AG (DE) | 2013-09-03 | — | — | US | claimed |
| US-20110163254-A1 | Hydrophilic Organofunctional Silicone Copolymers | WACKER CHEMIE AG (DE) | 2011-07-07 | — | — | US | claimed |
| US-20080207825-A1 | Hydrophilic Organofunctional Silicone Copolymers | WACKER CHEMIE AG (DE) | 2008-08-28 | — | — | US | claimed |
| US-8524849-B2 | Hydrophilic organofunctional silicone copolymers | WACKER CHEMIE AG (DE) | 2013-09-03 | — | — | US | disclosed |
| US-20110163254-A1 | Hydrophilic Organofunctional Silicone Copolymers | WACKER CHEMIE AG (DE) | 2011-07-07 | — | — | US | disclosed |