Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22022374 | 0.86 | APP (0.39) | APPERCC5FEN1SCN1AKCNH2 | |
| SCHEMBL16546593 | 0.73 | APP (0.44) | APPERCC5FEN1SCN1AKCNH2 | |
| SCHEMBL21774728 | 0.72 | APP (0.36) | APPERCC5FEN1PRF1 | |
| SCHEMBL16546541 | 0.72 | APP (0.36) | APPERCC5FEN1 | |
| SCHEMBL19798720 | 0.71 | APP (0.31) | APPERCC5FEN1 | |
| SCHEMBL21134077 | 0.71 | APP (0.40) | APPERCC5FEN1SCN1AKCNH2 | |
| SCHEMBL16549433 | 0.70 | FEN1 (0.41) | APPERCC5FEN1SCN1AKCNH2 | |
| SCHEMBL16546578 | 0.68 | APP (0.49) | APPERCC5FEN1SCN1AKCNH2 | |
| SCHEMBL20368685 | 0.65 | GCK (0.35) | APP | |
| SCHEMBL20182371 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487955-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-05-20 | — | — | EP | disclosed |