Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.80 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.80 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15587163 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549584 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549893 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL28436535 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549582 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16819283 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15550912 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549892 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549891 | 1.00 | PTGER4 (0.80) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15549258 | 0.89 | PTGER4 (1.00) | PTGER4PTGER2PTGER3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176162-B1 | DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS | CAYMAN CHEMICAL CO INC (US) | 2020-05-27 | — | — | EP | disclosed |