⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23863602 | 0.76 | — | — | |
| SCHEMBL28972627 | 0.73 | — | — | |
| SCHEMBL6032941 | 0.71 | — | — | |
| SCHEMBL14498518 | 0.69 | — | — | |
| SCHEMBL14958753 | 0.69 | — | — | |
| SCHEMBL2273057 | 0.67 | — | — | |
| SCHEMBL20978381 | 0.67 | — | — | |
| SCHEMBL24925671 | 0.67 | — | — | |
| SCHEMBL22485370 | 0.65 | — | — | |
| SCHEMBL7559868 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11248000-B2 | Quinazoline and indole compounds to treat medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| US-20200165262-A1 | Quinazoline and Indole Compounds to Treat Medical Disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2020-05-28 | — | — | US | disclosed |