Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.86 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.86 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16819550 | 1.00 | PTGER4 (0.86) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16819547 | 1.00 | PTGER4 (0.86) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15586958 | 1.00 | PTGER4 (0.86) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16819545 | 1.00 | PTGER4 (0.86) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL19328484 | 1.00 | PTGER4 (0.86) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL18257010 | 0.95 | PTGER4 (0.78) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL22024722 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16819583 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL22024934 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15587028 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176162-B1 | DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS | CAYMAN CHEMICAL CO INC (US) | 2020-05-27 | — | — | EP | disclosed |