Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914006 | 0.89 | KCNH2 (0.39) | KDM1A | |
| SCHEMBL19891744 | 0.80 | MAPK1 (0.35) | KDM1A | |
| SCHEMBL22792822 | 0.79 | EPHX1 (0.39) | EPHX1POLB | |
| SCHEMBL18617006 | 0.78 | SMYD3 (0.32) | KDM1A | |
| SCHEMBL4623461 | 0.75 | EPHX2 (0.36) | — | |
| SCHEMBL21973283 | 0.75 | CPN1 (0.32) | — | |
| SCHEMBL13731105 | 0.71 | EPHX1 (0.43) | EPHX1POLBKDM1A | |
| SCHEMBL24332147 | 0.70 | — | — | |
| SCHEMBL18874420 | 0.70 | TP53 (0.44) | EPHX1KDM1A | |
| SCHEMBL24046271 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136325-B2 | Pyrrolopyrimidine and pyrrolopyridine derivatives | GALAPAGOS NV (BE) | 2021-10-05 | — | — | US | disclosed |
| US-20200165259-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES | GALAPAGOS NV (BE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165259-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES | IRAK1, PEAK1, MARK1 | EPHX1 469/4885POLB 1702/4885KDM1A 609/4885 |
| US-11136325-B2 | Pyrrolopyrimidine and pyrrolopyridine derivatives | IRAK1, PEAK1, MARK1 | EPHX1 469/4885POLB 1702/4885KDM1A 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.