Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 5/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GLB1 | P16278 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894746 | 1.00 | OGA (0.46) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL2202670 | 1.00 | OGA (0.46) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL2202664 | 1.00 | OGA (0.46) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL2244048 | 1.00 | OGA (0.46) | OGAMAN1B1FUCA1GBA1GLA | |
| Hydrochloric Acid SCHEMBL2201669 | 0.98 | OGA (0.44) | OGAMAN1B1FUCA1GBA1GLA | |
| Hydrochloric Acid SCHEMBL2201680 | 0.98 | OGA (0.44) | OGAMAN1B1FUCA1GBA1GLA | |
| Hydrochloric Acid SCHEMBL2201677 | 0.98 | OGA (0.44) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL2272527 | 0.88 | OGA (0.51) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL2434063 | 0.88 | OGA (0.51) | OGAMAN1B1FUCA1GBA1GLA | |
| SCHEMBL15521047 | 0.88 | OGA (0.51) | OGAMAN1B1FUCA1GBA1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977358-B2 | Pyrazol derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-07-12 | — | — | US | disclosed |